The 3400 DNA Synthesizer is an economical, versatile platform that automates all steps of single-stranded oligonucleotide synthesis.

Overview:

The 3400 DNA Synthesizer is a highly versatile, four column, bench-top instrument designed for 40-nmol, 200nmol and 1-µmol synthesis scales. Simultaneous synthesis and cleavage of four oligonucleotides requires less than 4 hours.

Automatic Phosphoramidites dilution, electronic synthesis monitoring and automatic cleavage provide a largely hands free operation. Instrument is also fully adaptable to special synthesis requirements with fully programmable cycles, functions and reagent path ways.

A patented valve block design, small-diameter reagent delivery lines, and logical placement of valves and bottles relative to the synthesis columns all result in efficient use of reagents and minimal per cycle waste at all synthesis scales.

PC Compatibility:

The 3400 DNA Synthesizer is PC compatible. Instead a router is provided for connecting the instrument to a local computer, from which you can use your Web browser to download and edit sequences from an HTML page.

Applications:

Support chemistries for synthesis of following:

• Single Stranded Oligonucleotides.
• Biologically active RNA.
• RNA/DNA Chimeras
• Phosphorothiote DNA
• 5’ Labelled Phosphoramidites (6-FAM, HEX & TET Dyes)
• Biotinylation (Biotin)
• Phosphorylation (Phosphalink Phosphor amidites)
• Amine Addition (TFA Amino link)

Consumables/Reagents for 3400 DNA Synthesizer:

Consumables:

Standard Reagents:

Cyanoethyl Phosphoramidites & Speciality Phosphoramidities Derivatives: