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MALDI TOF/TOF Analyzer

Model : 4800 MALDI TOF/TOF Analyzer
Make : Applied Biosystems, USA
Location: Proteomics Lab
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Overview:

The 4800 MALDI TOF/TOF Analyzer is a floor standing Mass Spectrometer that delivers high resolution and accurate mass determination for the MS analysis of biomolecules including protein digests, intact proteins, lipids, and carbohydrates. The system also enables the precise selection of individual precursor masses for further fragmentation enabling definitive identification and characterization for these biological molecules by MS/MS. Featuring breakthrough optics and powerful, easy-to use software, the versatile 4800 ‎system offers confident, high productivity protein identification and Quantitation for all your discovery applications enabling routine use by expert and non-expert operators.

Applications:

  • Biomarker Discovery
    Protein ID and Quantitation
  • Protein ID
    Includes both MS and MS/MS techniques.
    ID of Protein in gel slices (routine ID from 1D, 2D gels).
    MDLC Fractions and complex samples with LC-MALDI.
  • Protein Expression Analysis
    ID and Quantification of Differen tially expressed proteins (iTRAQTM and ICAT® Reagents)
  • Protein Characterization
    Characterization of phosphorylation and glycosylation peptides by MS & MS/MS techniques. Intact Protein Analysis
  • Carbohydrates, lipids oligosaccharides, etc.