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List of Published Papers:

2012, until March (publication nos. 60-54, n = 7):

60. Al-Mulla F, Bitar MS, Feng J, Park S, Yeung KC. A new model for raf kinase inhibitory protein induced chemotherapeutic resistance. PLoS One. 2012;7: e29532.

59. Al-Turab M, Chehadeh W, Al-Mulla F, Al-Nakib W. Evaluation of the PrimerDesign™ genesig real-time reverse transcription-polymerase chain reaction assay and the INFINITI® Respiratory Viral Panel Plus assay for the detection of human metapneumovirus in Kuwait. Diagn Microbiol Infect Dis. 2012; PMID:22300956.

58. Benov L, Craik J, Batinic-Haberle I. Protein damage by photo-activated Zn(II) N-alkylpyridylporphyrins. Amino Acids. 2012;42:117-128.

57. Mehdawi H, Alkhalaf M, Khan I. Role of Na+/H+ exchanger in resveratrol-induced growth inhibition of human breast cancer cells. Med Oncol. 2012;29: 25-32.

56. Mustafa AS. What’s new in the development of Tuberculosis vaccines. Med Princ Pract 2012;DOI: 10.1159/000337919.

55. Narayana K, Al-Bader M, Mousa A, Khan KM. Molecular effects of chemotherapeutic drugs and their modulation by antioxidants in the testis. Eur J Pharmacol. 2012;674: 207–216.

54. Rahman A, Khan KM, Al-Khaledi G, Khan I, Al-Shemary T. Over activation of hippocampal serine/threonine protein phosphatases PP1 and PP2A is involved in lead-induced deficits in learning and memory in young rats. Neurotoxicology. 2012; 33: 370-383.

2011 (publication nos. 53-32, n = 22):

53. Al-Awadhi R, Chehadeh W, Jaragh M, Al-Shaheen A, Sharma P, Kapila K. Distribution of Human Papillomavirus Among Women with Abnormal Cervical Cytology in Kuwait. Diagnostic Cytopathology. 2011. DOI: 10.1002/dc.21778

52. Al-Awadhi R, Chehadeh W, Kapila K. Prevalence of human papillomavirus among women with normal cervical cytology in Kuwait. J Med Virol. 2011;83: 453-60.

51. Alawadi S, Ghabreau L, Alsaleh M, Abdulaziz Z, Rafeek M, Akil N, Alkhalaf M. P53 gene polymorphisms and breast cancer risk in Arab women. Med Oncol. 2011;28: 709-715.

50. Al-Dashti A, Jadaon MM. Race differences in the prevalence of the factor V Leiden mutation in Kuwaiti nationals. Mol Bio Rep. 2011;38: 3623-3628.

49. Al-Humood SA, Al-Qallaf AS, Francis IA, Al-Shemmari SH, Junaid TA, Marouf RA, Al-Mulla F. Genotypic and Phenotypic Differences between Nodal and Extranodal Diffuse Large B-Cell Lymphomas. J Histochem Cytochem. 2011;59: 918-931.

48. Al Khaldi RM, Al Mulla F, Al Awadhi S, Kapila K, Mojiminiyi OA. Associations of single nucleotide polymorphisms in the adiponectin gene with adiponectin levels and cardio-metabolic risk factors in patients with cancer. Dis Markers. 2011;30: 197-212.

47. Al-Mulla F. Microarray-based CGH and copy number analysis of FFPE samples. Methods Mol Biol. 2011;724: 131-145.

46. Al-Mulla F, Bitar MS, Al-Maghrebi M, Behbehani AI, Al-Ali W, Rath O, Doyle B, Tan KY, Pitt A, Kolch W. Raf Kinase Inhibitor Protein RKIP Enhances Signaling by Glycogen Synthase Kinase-3 β. Cancer Res. 2011;71: 1334-1343.

45. Al-Mulla F, Bitar MS, Taqi Z, Rath O, Kolch W. RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility. Mol. BioSyst. 2011;7: 928–941.

44. Al-Mulla F, Leibovich SJ, Francis IM, Bitar MS. Impaired TGF-β signaling and a defect in resolution of inflammation contribute to delayed wound healing in a female rat model of type 2 diabetes. Mol Biosyst. 2011;7: 3006-20.

43. Al-Saeedi FJ, Bitar MS, Pariyani S. Effect of Asiaticoside on 99mTc-Tetrofosmin and 99mTc-Sestamibi Uptake in MCF-7 Cells. J Nucl Med Technol. 2011;39: 279-283.

42. Al Saleh S, Al Mulla F, Luqmani YA. Estrogen receptor silencing induces epithelial to mesenchymal transition in human breast cancer cells. PLoS One. 2011;6: e20610.

41. Al Saleh S, Sharaf LH, Luqmani YA. Signalling pathways involved in endocrine resistance in breast cancer and associations with epithelial to mesenchymal transition. Int J Oncol. 2011;38: 1197-217.

40. Al-Shamali A, Khan I, Expression of Na–H exchanger-8 isoform is suppressed in experimental colitis in adult rat: lack of reversibility by dexamethasone. Isoforma. 2011;46: 20-29.

39. Al-Turab M, Chehadeh W, Al-Mulla F, Al-Nakib W. Human metapneumovirus in patients with respiratory tract infection in Kuwait. J Med Virol. 2011;83: 1811-1817.

38. Bitar MS, Al-Mulla F. A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes. Am J Physiol Endocrinol Metab. 2011;301: E1119-129.

37. Bosso M, Al-Mulla F. Whole genome amplification of DNA extracted from FFPE tissues. Methods Mol Biol. 2011;724: 161-80.

36. Dallol A, Al-Ali W, Al-Shaibani A, Al-Mulla F. Analysis of DNA methylation in FFPE tissues using the MethyLight technology. Methods Mol Biol. 2011;724: 191-204.

35. Kehinde E, Al-Mulla F, Kaplia K & Anim J. Comparison of the sensitivity and specificity of urine cytology, urinary nuclear matrix protein-22 and multitarget fluorescence in situ hybridization assay in the detection of bladder cancer. Scandinavian J Urol Nephrol. 2011;45: 113–121.

34. Kusum Kapila, S Al-Awadhi, and IM Francis. Her-2 neu (Cerb-B2) expression in fine needle aspiration samples of breast carcinoma: A pilot study comparing FISH, CISH and immunocytochemistry. J Cytol. 2011;28: 54–56.

33. Matallanas D, Romano D, Al-Mulla F, ONeill E, Al-Ali W, Crespo P, Doyle B, Nixon C, Sansom O, Drosten M, Barbacid M, Kolch W. Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. Mol Cell. 2011;44: 893-906.

32. Thomas M, Benov L. Cell-based biassay for compounds with prooxidant activity. Environ Health Biomed. 2011;DOI:10.2495/EHR110161.

2010 (publication nos. 31-22, n = 10):

31. Alawadi S, Ghabreau L, Alsaleh M, Abdulaziz Z, Rafeek M, Akil N, Alkhalaf M. P53 gene polymorphisms and breast cancer risk in Arab women. Med Oncol. 2010;28: 709-715.

30. Alkhalaf M, Al-Shoumer K. Cytogenetic abnormalities and azoospermia factor (AZF) microdeletions in infertile men from Kuwait. J Mol Genet Med 2010;4: 232-234.

29. Bitar MS, Ayed AK, Abdel-Halim S, Isenovi E, Al-Mulla F. Inflammation and apoptosis in aortic tissues of aged type 2 diabetes: amelioration with á-lipoic Acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism. Life Sciences. 2010;86: 844-853.

28. Dashti AA, Jadaon MM, Amyes SG. Retrospective study of an outbreak in a Kuwaiti hospital of multidrug-resistant Klebsiella pneumoniae possessing the new SHV-112 extended-spectrum beta-lactamase. J Chemother. 2010;22: 335-338.

27. Dashti AA, Jadaon MM, Gomma HH, Noronha B Udo EE. Transmission of a Klebsiella pneumonia clone harboring genes for CTX-M-15-like and SHV-112 enzymes in a neonatal ICU of a Kuwaiti hospital. J Med Microbiol. 2010;59: 687-692.

26. Dashti AA, Jadaon MM, Lewis HL. Factor V Leiden mutation in Arabs in Kuwait by real-time PCR: Different values for different Arabs. J Human Genetics. 2010;55: 232-235.

25. Dimitrov T, Dashti AA, Albaksami O, Jadaon MM. Detection of Mutation in the gyrA gene in Fluoroquinolone resistant Salmonella enteric serotypes typhi and paratyphi A isolated from Infectious Disease Hospital, Kuwait. J Clin Pathol. 2010;63: 83-87.

24. Ezeamuzie CI, Shihab PK. Interactions between theophylline and salbutamol on cytokine release in human monocytes. J Pharmacol Exp Ther. 2010;334: 302-309.

23. Islam A, Raghupathy R, Albert J. A recombinant PorA, the major outer membrane protein (MOMP) of Campylobacter jejuni provides heterologous protection in an adult mouse intestinal colonization model. Clin Vaccine Immunol. 2010;17: 1666-1671.

22. Mojiminiyi OA, Safar FH, Al Rumaih H, Diejomaoh M. Variations in alanine aminotransferase levels within the normal range predict metabolic and androgenic phenotypes in women of reproductive age. Scand J Clin Lab Invest. 2010;70: 554-60.

2009 (publication nos. 21-17, n = 5):

21. Al Dashti A, Jadaon M, Abdulsamad A, Dashti H. Heat Treatment of Bacteria : A simple method of DNA Extraction for Molecular Techniques. Kuwait Med J. 2009;41: 117-122.

20. Khan I, Batinic- Haberle I, Benov L. Effect of potent redox-modulating manganese porphyrin, MnTM – 2- PyP, on the Na+/H+ exchangers NHE-1 and NHE-3 in the diabetic rat. Redox Report. 2009;14: 236-242.

19. Kos I, Benov L, Spasojevic I, Reboucas J, Batinic-Heberle I. High Lipophilicity of meta Mn(III) N-Alkylpyridylporphyrin-Based Superoxide Dismutase mimics compensates for their lower Antioxidant Potency and Makes Them as Effective as Ortho analogues in protecting superoxide dismutase deficient Escherichia coli. J. Med. Chem. 2009;52: 7868 – 7872 .

18. Luqmani Y, AL Azmi A, AL Bader M, Abraham G, EL Zawahri M. Modification of gene expression induced by siRNA targeting of estrogen receptor in MCF7 human breast cancer cells. Int J Oncol 2009;34: 231-242.

17. Masocha W. Systemic lipopolysaccharide (LPS) induced microglial activation results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain. J Neuroimmunol. 2009;214: 78-82.

2008 (publication nos. 16-12, n = 5):

16. Al-Dashti A, Jadaon M, Habeeb F, West PW, Panigrahi D, Amyes SG. Salmonella enterica Serotype typhi in Kuwait and its reduced susceptibility to ciprofloxacin. J Chemother. 2008;20: 297-302.

15. Al-Mulla F, Hagan S, Al-Ali W, Jacob S, Behbehani A, Bitar MS, Dallol A, Kolch W. Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability. J Clin Pathol. 2008;61: 524-529.

14. Batinic -Haberle I, Benov L. An SOD mimic protects NADP+ - dependent isocitrate dehydrogenase against oxidative inactivation. Free Radical Research. 2008;42: 618-624.

13. Kapila K, Kehinde EO, Anim JT, Mojiminiyi OA, Vinsu A, George SS, Al-Maghrebi M, Al-Mulla F. Could nuclear matrix protein 22 (NMP22) play a role with urine cytology in screening for bladder cancer?--experience at Kuwait University. Cytopathology. 2008;19: 369-74.

12. Malatiali S, Francis I, Barac-Nieto M. Phlorizin Prevents Glomerular Hyperfiltration but not Hypertrophy in Diabetics Rats. Experimental Diabetes Research. 2008; ID-305403.

2007 (publication nos. 6-11, n = 6):

11. Al-Benwan K, Abbott S, Janda J, Huys G, Albert J. Cystitis Caused by Aeromonas caviae. Journal of Clinical Microbiology. 2007;45: 2348-2350.

10. Al-Mutairi D, Craik J, Batinic-Heberle I, Benov L. Inactivation of Metabolic Enzymes by Photo-treatment with Zinc meta N-Methylpylporphyrin. Biochimicz Et Biophysica Acta. 2007;1770: 1520-1527.

9. Al-Mutairi D, Craik J, Batinic-Heberle I, Benov L. Induction of Oxidative Cell Damage by Photo-treatment with Zinc meta N-Methylpylporphyrin. Free Radical Research. 2007; 41: 89-96.

8. Al Zaid N, Dashti H, Mathew T, Juggi J. Low Carbohydrate Ketogenic Diet Enhances Cardiac Tolerance to Global Ischaemia. Acta Cardiol. 2007;62: 381-389.

7. El Shazly S, Ahmed S, Mustafa AS, Al Attiyah R, Krajci D. Internalization by HeLa cells of latex Beads Coated with Mammalian Cell Entry (Mce) Proteins Encoded by the mce3 operon of Mycobacterium tuberculosis. J Med Microbiol. 2007;56: 1145-1151.

6. Kodousek R, Jezdinsky J, Krajci D. Histological & Ultrastructural Changes of Cardiomyocytes in Experimental Rats with Tail Thrombosis following Subplantar Application of Carrageenin. Med. Princ. Pract. 2007;16: 360-366.

2006 (publication nos. 1-5, n = 5):

5. Al-Enezi KS, Al Khalaf M, Benov L. Glycolaldehyde Induces Growth Inhibition & Oxidative Stress in Human Breast Cancer Cells. Free Racal Biology & Medicine. 2006; 40: 1144-1151.

4. Al-Mutairi D, Craik J, Batinic-Heberle I, Benov L. Photosensitizing Action of Isomeric Zinc meta N-Methylpylporphyrins in Human Carcinoma Cells. Free Racal Research. 2006;40: 477- 483.

3. Al-Mulla F et al. Raf Kinase Inhibitor Protein Expression in a Survival Analysis of Colorectal Cancer Patients. J. Clin. Oncol. 2006;24: 5672 – 5679.

2. Jadaon MM, Al-Dashti A, Lewis H L. Factor V Kuwait: A Novel Mutation in the Coagulation Factor V Gene Discovered in Kuwait. Med Princ Pract. 2006;15: 102-105.

1. Krajci D, Mares V, Lisa V, Bottone M G & Pellicciari C. Intranuclear Microtubules are Hallmarks of an unusuall form of Cell Death in Cisplatin-treated C6 Glioma Cells. Histochem Cell Biol. 2006;125: 183-191.