The Research Core Facility (RCF) is an integrated laboratory, housing state-of-the-art equipment and instruments, essentially required by researchers in implementing their research at HSC, Kuwait University. The RCF equipment is operated by qualified and trained staff.The instrumentation essentially meets the requirements of most research projects. Invariably, the cost of instruments, concerning individual research proposals, prove a stumbling block in project approval. In addition, a remarkable development has been observed as regards the emergence of new technologies and sophisticated instrumentation, that are immensely powerful, and facilitate in depth study of disease processes at cellular and molecular levels. These core facilities stimulate faculty and staff expertise, encouraging them to develop specialized techniques for utilizing the advanced equipment resource, and to make them available to HSC students and faculty.